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If a unit is issued at, say, 2210 and the specimen (not the unit) will expire at MN, do they have to stop the transfusion at MN or is it okay to finish giving the unit if it isn't quite done by MN? We use MN on day 3 as our crossmatch/specimen expiration (not exactly 72 hours) so theoretically a specimen even in normal circumstances could be over 90 hours hours old at the time of a transfusion if it was drawn very early in the morning. I am convinced that medically it won't "turn into a pumpkin" at MN but what do you think inspectors would say? Do you have a hard and fast policy for this or leave it up to judgment? Is it okay to issue a unit on an expiring specimen as long as issuing occurs before the specimen expires, the infusion will start by the time the specimen expires, or only if the entire infusion can be completed by the time the specimen expires?