Hi Colleen, I do not think that there has been any study that establishes clearly that autologous cryo works better than allogeneic. However, I have heard similar, but not proven, comments about platelet gel. The use of an autologous product is mostly driven by the avoidance of virus risks from allogeneic sources. There has been a recent review paper (European Cells and Materials Vol 8, 2004, pp 1-11) discussing experimental studies of ceramics/fibrin glue composites and speculating that some failures in animal experiments may be due to the use of cryo from another species, while cryo from the same species works better. Thierry Burnouf, PhD HPPS 18 rue Saint-Jacques 59000 Lille France