We do not perform computer crossmatch here and I am very interested about computer crossmatches. I've asked a friend of mine who is SBB, he said the way the guidance is written if clinically significant antibodies are not detected then you can rely on computer crossmatch but if there is ABO typing problem you can not. As for performing IS in addition to gel, he said blood bankers have different opinions but those who get inspected by AABB and FDA will definitely perform IS to be compliant.