Thanks for the information. We just recently had a similar incident with an Anti-C. We had a patient that Immucor was picking up a positive antibody screen and the ID showed an Anti-D. When we were testing with the Tango it also picked up a positive antibody screen, but the ID was both Anti-D, and Anti-C. Immucor did not pick up the Anti-C. Both Immucor, and Biotest antisera were C negative, but we had gone for 5 years not picking up the Anti-C in this patient's serum. We do have one patient with Anti-U, but we refer it to Red Cross Reference for units and workups. We don't have much use for S typing. However, I will certainly keep this information as it may come in handy. Also, the cell that identified the Anti-C reacted at 2+ with the Tango, yet negative with Immucor.?? Thanks for the information. John