We purchased 2 Echos this year. Prior to that we were using the Ortho gel. We had absolutely no trouble making the transition, even though the idea had been met with a greal of resistance by several techs prior to implementation. I would not factor the change in methodology into my decision if I were you. When using the Ortho gel, we had trouble with a higher than average number of patients with non-specific colds...and we have the same percentage now with Immucor. Same goes with the patients who react to the additives in the gel/plates...the number is the same now as it was when we were using the gel. Like you, we seriously looked at both the Echo and the Provue. Our decision was based on ease of use, downtime, difficulty of maintenance, and price. It was a tough decision, but we eventually decided to go with the Echos for these reasons. We have had no trouble with the transition, and no regrets regarding our decision. In fact, the techs who were most resistant to the change are now the Echos' biggest fans.