In my POCT career I've used all of the middleware products and your best bets for flexibility of devices is either Telcor or RALS. We currently have Gluocse, Hemocue, I-STAT, Hepcon, Medtronic ACT Plus, DCA Vantage and the Clinitek connected to Telcor. It is very helpful as we are a 1000 bed hospital. The problem with vendor specific systems (such as Pweb) is that they claim they can connect any vendor, but our experience was that it is never completely true. Best to go with a neutral party.