safars Posted February 2, 2006 Share Posted February 2, 2006 We test a 6% albumin control for all new AB Pos patients to rule out polyagglutination. I don't think this is now necessary since our monoclonal typing reagents should not pick up polyagglutination. Any comments? Link to comment Share on other sites More sharing options...
Lcsmrz Posted February 2, 2006 Share Posted February 2, 2006 I would follow the recommendation of the product insert of the reagent mfr.Not sure what ours says. Some things are just hard to give up emotionally ... Link to comment Share on other sites More sharing options...
Kochman Posted February 7, 2006 Share Posted February 7, 2006 It is still prudent to run some kind of control when a donor/patient types as AB pos. While it it is true that the new monoclonals are less likely to react non-specifically due to things like polyagglutination, there are occassional reports of false positives due to a component of the reagent diluent. The ideal control would be the reagent diluent itself but I'm not certain it is always available.As far as following the manufacturers' package insert, don't assume that if the manufcturer does not describe such a control that it is not necessary. Remember, it might be required by some local/state/federal agency even if it's not in the PI. Link to comment Share on other sites More sharing options...
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