On sysmex Xn 1000,  we could get WBC count by the WDF channel. So could we run CBC  without WNR reagent?

I don't think the XN will allow you to run without the WNR reagent. You wouldn't be able to get an automated differential because the basophil count comes from the WNR. Also, the NRBCs come from the WNR channel, so any WBC count from the WDF channel would also include NRBCs.