Search the Community
Showing results for tags 'excusion of antibody'.
Found 1 result
-
From: Guidelines for Antibody Identifcation, American Association of Blood Banks, 2010. Additional Guidance and Testing, page 21 "2. Exclusion of anti-E and anti-C may be completely eliminated for patient with anti-c and anti-e, respectively, because of the paucity of c-E+ and e-C+ donor units. Policies do differ in this regard. a. In addition to selecting donor units lacking the antigen(s) corresponding to the known antibody(ies), select donor units lacking the antigen(s) for which antibody exclusion has not been performed. For example, select c-E- units with anti-c and C-e- units with anti-e, even though c-E+ or C+e- red cells were not tested and the presence or absence of anti-E or anti-C, respectively, is unknown. b. Select donor units lacking the antigen(s) corresonding to the known antibody(ies). When transfusion is requested, an antiglobulin crossmatch of the appropriate antigen-negative donor cells will be required (ie, c- or e- units would be crossmatched). If the patient also had anti-E or anti-C, not excluded by antibody identification testing, antigen-positive donor unit would be incompatible." Which policy do you follow, A or B? ( assume, that in either case, antiglobulin crossmatch is done.) Thanks, Dan
