We have a issue that has been up for discussion lately at my facility regarding identifying antibodies as cold agglutinins. Per (new) supervisor, if we rule out all allos on the abid panel and our auto control is negative, we should perform a prewarm screen and if it is negative, identification is documented as "cold agglutinin". We then perform prewarm crossmatches for the patient. I have seen this policy before at a previous facility I worked at, but this is new to some of the techs at my current facility. And because I have been at current facility for several years now and followed the policy of the recently retired supervisor of identifying everything or sending it to the reference lab, it now makes me a little uncomfortable too. The claim by some is that there are specific tests available for identifying cold agglutinins and that we shouldn't just call them that without doing these additional tests. Another claim is that the hematology sample would have erroneous indices if a true cold agg was present but it did not. Any input from the bb gurus on this? (Ortho gel panel A and B were ran along with the initial gel screen where there were multiple 1-3+ reactions but all allos were ruled out using at least 3 homozygous cells. Auto control negative.)