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Showing results for tags 'ficin'.
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I have read an article from last year about a lab that routinely runs a gel enzyme panel when they get equivocal results (i.e. antibodies of undetermined significance, AUS's, non-specific reactions) on gel screens or panels. About 25% of the time they identified significant allo-antibodies that otherwise would have been missed as they would have been ruled-out on the regular panels. Does anyone else do this? https://academic.oup.com/labmed/article/48/1/24/2666003 Thanks, Scott -
The following article from Lab Medicine discusses the idea of routinely using enzyme treatment to enhance non-specific (we call them equivocal) antibody reactions. The idea is that some of the reactions we end up calling non-specific (where remaining significant alloantibodys have been all ruled out) may be actualkly developing significant alloantibodys. https://academic.oup.com/labmed/article-abstract/48/1/24/2666003/Ficin-Treated-Red-Cells-Help-Identify-Clinically?redirectedFrom=fulltext Other than reference labs, does anyone routinely try to otherwise enhance reactions to see if a non-specific pattern turns into a specific one? Thanks, Scott
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The following article from Lab Medicine discusses the idea of routinely using enzyme treatment to enhance non-specific (we call them equivocal) antibody reactions. The idea is that some of the reactions we end up calling non-specific (where remaining significant alloantibodys have been all ruled out) may be actualkly developing significant alloantibodys. https://academic.oup.com/labmed/article-abstract/48/1/24/2666003/Ficin-Treated-Red-Cells-Help-Identify-Clinically?redirectedFrom=fulltext Other than reference labs, does anyone routinely try to otherwise enhance reactions to see if a non-specific pattern turns into a specific one? Thanks, Scott