We have had several Rh positive patients (4-5) in the past week that exhibt reactions that mimic anti-D in Ortho VRA190 gel testing. These patients have reactions with 4 out of the 5 Rh positive cells. All clinically significant antibodies are ruled out. One patient did end up having a warm autoantibody with anti-D specificity, but all of the others have had negative autocontrols. We end up calling them "undetermined" and perform AHG crossmatch. Wondering if anyone has had similar issues with this panel. Thanks.
