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The loosened belt and less vigorous shake should increase the sensitivity of the hemagglutination based reactions, especially the reverse ABO group. Our belt actually loosened with use and had to be tightened to completely resuspend negative reactions - we were getting too many false positives. Hope the loosened belt helps resolve some of your NTD's and NO INTERP's.
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That is also a concern. As the tungsten bulb deposits graphite on the inner glass surface with aging, the light emission changes and we start seeing more discrepant results. When the Immucor service person arrives, they turn the gain up on the lamp and we are OK for a while. We are getting used to dealing with this problem. As mentioned in the previous threads, there is also lot-to-lot variability in reagents and controls. The bulb adjustment and reagent variability are monitored by carefully looking at our NTD and Equiv. incidence. When we see adverse trends, we are on the phone to Immucor. What we are a little nervous about is the additive affect of the two problems.
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Immucor is having personnel turnover issues. The inventor of Capture and original management are all retired. The main production manager for red cells, who is responsible for dried RBC plates and Indicator Cells is retiring this month. The new replacement personnel are on a learning curve and new senior management has no experience with solid phase or serology. I am afraid that these issues may continue. Immucor is pretty good about reagent replacements, but I know my lab will be spending more time resolving these issues. I hope the new Immucor personnel come up to speed quickly.