Hi, John, About benchmark data for transfusion reactions, I would caution that they are particularly hard to benchmark meaningfully since there are many factors that affect transfusion reaction rate, including * patient population (particularly the % of multi-transfused patients, who would be expected to have higher rates) * % of patients transfused with platelets (rates are much higher for this group) * how rigorous the criteria are that are used to define what consitutes a reaction (facilities that look for them using defined criteria would be expected to have higher rates; different criteria would produce different reaction rates) * type of product transfused (facilities transfusing ony leukoreduced products may have lower rates) For rates to be applicable facilites should be relatively closely matched these factors. Cheers, Pat