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I apologize for the delay in communication. I am at a small hospital in the transfusion medicine department. We send out all of our positive antibody screens. I received the results of the workup yesterday. I should have mentioned that I performed both gel and tube screens and both were negative. I also attempted reverse typing with a different lot # of A1 cells. I have the same results. The antibody identification results from our reference lab showed that she has anti-A1 and types as A2B. Unfortunately, she gave birth before we could get those results. I had a fear that the baby could be A1B if the father was A1. The father was actually O pos. I later typed the baby as B pos. Phew! Currently our policy is to ask pregnant women with an antibody to have an antibody titer done throughout the pregnancy. Does anyone have policies for anti-A1 titers for pregnant women? I imagine it should only be done if anti-A1 reacts through AHG phase. Thanks for your suggestions!
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I recently had a woman come into labor and delivery who forwards are as listed A-4+ B-4+ Reverse anti-A-1+ Anti-B-0 I have subsequently ordered a new type and screen to get the same results. I suspect one fo two things she is a A subgroup B patient or she has been sensitized during pregnancy to some other A subgroup. I am using tube method and checked for rouleaux. Does this seem feasible any suggestions to resolve this?
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We used velcro and modified the clear A1 and B cell boxes as covers to keep them from getting damaged, as they often do in transport.
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I am a long time lurker and this is my first post. I am looking up research for a project and I wanted to get some information from those in the field. Does anyone know if there has been a study that has examined hemoglobin a1c levels and additive solutions? There are lots of studies that suggest that transfusion of older blood (>25 days) to patients have increased negative outcomes. There is no link to hemoglobin a1c and anticoagulants but I can't find any papers on the effects of additive solutions to hemoglobin levels.