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Bijoux71

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    Bijoux71 got a reaction from carolyn swickard in Does this blood bank "critical thinking" question makes sense to anyone?   
    In scenarios like this, questions and possibilities that first come to mind are the following, not in any specific order:
     
    1.) The DAT of the donor unit is extremely relevant.  Yes, DATs are not routinely run on all donors however, when IRL testing discovers a discrepant IAT antigen type, Rh or other, a positive DAT is often the culprit.  If the discrepant type is at immed spin or direct agglutination, several possibilities come to mind, such as a bacterial contaminated donor unit which may cause spontaneous agglutination, or a medicine that donor takes and is not screened for or donor doesn't give an accurate reply to pre-donation questions, or a donor with a cold agglutinin.
    2.) Some previous posts have stated that most current Anti-D reagents will not detect DVI.  I feel like that statement is confusing and should be worded to say "most Anti-D reagents will not detect type DVI by direct agglutination, but are able to detect DVI at IAT. 
     
  2. Like
    Bijoux71 got a reaction from Yanxia in Does this blood bank "critical thinking" question makes sense to anyone?   
    In scenarios like this, questions and possibilities that first come to mind are the following, not in any specific order:
     
    1.) The DAT of the donor unit is extremely relevant.  Yes, DATs are not routinely run on all donors however, when IRL testing discovers a discrepant IAT antigen type, Rh or other, a positive DAT is often the culprit.  If the discrepant type is at immed spin or direct agglutination, several possibilities come to mind, such as a bacterial contaminated donor unit which may cause spontaneous agglutination, or a medicine that donor takes and is not screened for or donor doesn't give an accurate reply to pre-donation questions, or a donor with a cold agglutinin.
    2.) Some previous posts have stated that most current Anti-D reagents will not detect DVI.  I feel like that statement is confusing and should be worded to say "most Anti-D reagents will not detect type DVI by direct agglutination, but are able to detect DVI at IAT. 
     
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