In scenarios like this, questions and possibilities that first come to mind are the following, not in any specific order:
1.) The DAT of the donor unit is extremely relevant. Yes, DATs are not routinely run on all donors however, when IRL testing discovers a discrepant IAT antigen type, Rh or other, a positive DAT is often the culprit. If the discrepant type is at immed spin or direct agglutination, several possibilities come to mind, such as a bacterial contaminated donor unit which may cause spontaneous agglutination, or a medicine that donor takes and is not screened for or donor doesn't give an accurate reply to pre-donation questions, or a donor with a cold agglutinin.
2.) Some previous posts have stated that most current Anti-D reagents will not detect DVI. I feel like that statement is confusing and should be worded to say "most Anti-D reagents will not detect type DVI by direct agglutination, but are able to detect DVI at IAT.
