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We do as your new supervisor states but without the DAT (unless the autocontrol is positive). An even when a patient has a history of let us say, little-c, we only run the cells that are little-c negative. By this time you should have done a screen and determined that little-c was still present. Anyway, this will allow you to waste time on cells that will ultimately be positive and not useful to rule out the other clinically significant antibodies. There is no need to re-identify little-c again anyway, since you have a history and are required to give little-c negative red cells.