Leaderboard

This is just my opinion. First, it's usually not a titer but a single-point dilution. What dilution? It's truly arbitrary. Some go 1:50, some 1:100, others 1:200. It depends on what the facility medical director will accept. Your colleague should collaborate with their medical director to determine what they feel is "safe". This cut-off will not prevent reactions, only minimize the risk. Then from there, it should be a simple procedure of a single-point dilution, with a cut of 1+, 2+... or less.

I agree with Bet'naSBB - the IS XM must be done in either tube or gel/other serologic method to verify ABO compatibility. Since a patient with a current or history of clinically significant antibody does not qualify for electronic crossmatch, the serologic version must be included with the AHG phase XM.