I understand that a lot of donor centers no longer produce non-additive RBCs and was wondering what product was being used for large volume neonatal RBC transfusions, including PUBs and whole blood exchanges.

I was sent an article about using AS3 for exchanges (attached), but our neonatologists want more data before they will agree to change.

 

 

neonatal exchange transfusions in the 21st century (3).pdf

Moderate-size pediatric hospital (about 450 beds):  We give adsol for all of our routine transfusions (10-20ml/kg).  We still use CPD/CP2D red cells for all large volume transfusions such as ECMO prime and open-heart surgery and make reconstituted whole blood (from CPD/CP2D red cells) for neonatal exchange transfusions.  It does sound like this is becoming more of a luxury, as many Transfusion Services are not FDA registered and making the RWB product.

Stephanie Townsend, MT(ASCP)SBB