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A2B blood type

kmmoton
in Transfusion Services

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comment_53464

If a patient is classified as A2B, should their reverse A1 cells always come up positive or is it possible for the reverse A1 cells to be negative?

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  • SMW
    SMW

    Only about 25% of A2B individuals will have an anti-A1 detected by routine ABO testing methods.

  • L106
    L106

    According to Peter Issitt's book Applied Blood Group Serology (paraphased):  Between 1 and 8% of A2 individuals produce Anti-A1, and approximately 22 and 35% of A2B individuals produce Anti-A1.   So,

comment_53475

Only about 25% of A2B individuals will have an anti-A1 detected by routine ABO testing methods.

    •
    comment_53476

    According to Peter Issitt's book Applied Blood Group Serology (paraphased):  Between 1 and 8% of A2 individuals produce Anti-A1, and approximately 22 and 35% of A2B individuals produce Anti-A1.

     

    So, it is very typical to not find Anti-A1 in the plasma of A2B patients.

     

     

    Donna

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