Does anyone still worry about this? We still have it in our procedure to give historically Lua Ag negative RBCs if we cannot demonstrate that the patient is not currently producing the antibody. Otherwise we just do a coombs XM on regular units.

Our reference lab does not even carry commercial anti-Lua anymore. They use human-source when they can get it if a customer insists on having units typed.

Thanks, Scott

We give ahgxm compatible when anti-Lua is present . . . have done this for decades.

We give ahgxm compatible when anti-Lua is present . . . have done this for decades.

Thanks, Dave. The question is what do you do when anti-Lua is NOT detected?

Scott

Thanks, Dave. The question is what do you do when anti-Lua is NOT detected?

Scott

We will continue to give AHG compatible units, even if it is not detectable. We may eventually start giving electronic crossmatch after review by pathologist.

R1R2

Still ahgxm compatible - I'm not purchasing Lua antisera. Its clinical significance appears to be insignificant.

We would give IAT cross-match compatible units that are NOT typed for either Lu(a) or Lu(, whether the anti-Lua is detectable or not.

Anti-Lua has never been implicated in either an immediate or a delayed haemolytic transfusion reaction.

Anti-Lua is a nuisance antibody, rather than a clinically significant antibody (see, amongst many, many other excellent textbooks written by the cream of blood group serologists, Reid ME, Lomas-Francis C, Olsson ML. The Blood Group Antigen FactsBook. 3rd Edition, 2012. Elsevier, page 271).

:peaceman::peaceman: