Current lot of Ortho screening cells, lot VS546 has given us very weak to weak 1+ reactions with 4 patients to date. When a panel or panels are run, no cells have reacted. If anyone else out there has had this experience would you please report to Ortho.

We are having that issue with VS548.

We have had that issue with lots VSS476, VSS478 and currently with VSS479. I called Ortho and they said that my staff were probably pipetting incorrectly and contaminating the cells with the IgG diluent in the cards. They said the cells probably have a positive DAT. We do negative controls daily and would have caught that. I am not happy with the response from Ortho, and am glad it isn't just me!