Hi

A pateint with macrogloubulinaemia, and has a strong IgM in his blood which didnt go with prewarmed tube method, I cant find compatible blood,, all the tests show strong agglutination even before adding AHG reagent,, we dont have DTT reagent to remove IgM from the plasma,,we transfused the patient with uncompatible but Rh group matching blood units a week ago and afraid that the patient developed alloantibodies,,, any ideas to how to remove IgM from the plasma:(:(

If you haven't got access to DTT, have you got access to rabbit erythrocyte stroma?

If you haven't got access to DTT, have you got access to rabbit erythrocyte stroma?

No am afraid not,,,

Hmmmmmmmm.............I'll have to think about this one, but nothing comes immediately to mind, except to send it to your Reference Laboratory.

No am afraid not,,,

Immucor has a product that uses rabbit erythrocyte stroma called REST for removal of colds

We send stuff like this to reference labs.

Immucor has a product that uses rabbit erythrocyte stroma called REST for removal of colds

That's the one I meant; just couldn't remember who made it.

That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own.

That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own.

Now there's a thought........................cheaper!

That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own.

I think Malcolm will do this, but more for the meat with a glas of wine then for the red cells.

with out the transfusion, a cold auto absorption would be nice but now you have to perform an allo-absorption.

Is the patient bloodgroup A? And if yes, is anti H or IH a possibility?

I do believe it could be relaxing to collect your own rabbit cells, then a hearty dinner, yum.

I think Malcolm will do this, but more for the meat with a glas of wine then for the red cells.

Strangely, for someone who is virtually a carnivore, rabbit meat is not to my taste - but the glass of wine - now your talking!!!!!!!!!!!!!!!

Edited May 17, 201213 yr by Malcolm Needs
STILL can't spell!!!!!!!!!!!!!!

you're

Couldn't resist, Malcolm.

you're

Couldn't resist, Malcolm.

As I've often said on this site, speling iz knot my strong point!!!!!!!!!!!!!!!!!!!!!

If the spelling of "your" and "you're" were a blood bank process we would redesign it because it is too prone to human error.