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Antibody Identification scenario #1

MeganPLT
in Immunohematology Reference Laboratories

What do you do in the following situation? 6 members have voted

  1. 1. What do you do in the following situation?

    • run screen on another methodology and if neg - report screen as negative
      1
    • report out "all clinically significant ab's rule out - or similar wording
      5
    • other - please describe in post
      0

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Posted
comment_40183

Solid phase is your primary method - you get a positive screen - let's say 1+ rxn on both, you run the ABID panel and auto/c or DAT and it's negative - what do you do?

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comment_40190

I wasn't asked to, but I will comment anyway.

We find that solid phase is far too sensitive, but not specific for such sensitivity.

As such, if it reacts by 1+ solid phase, but not by other technologies, and one of your screening cells is Jk(a+b-) and the other Jk(a-b+), then it's not going to be clinically significant anyway (at least, until the antibody has been boosted).

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