I am in doubt of who taking history and examine our donors before donation and also sometimes cross match test becomes positive due to DAT positive of Bags, Shall I do DAT routinely for all blood units?

In the UK, the Blood Services no longer perform a DAT on all units, but, occasionally one is identified during a cross-match.

With electronic issue and "immediate spin" cross-match, it is highly likely that, at some point, a unit that is DAT positive has been transfused to a patient. We are unaware of any untoward incident as a result of this happening.

With the Gel crossmatch we do find DAT positive units...I would say we had three in last three month...

The donor is a healthy or looks like healthy one, his or her DAT pos not cause himself anemia, then would it cause the cells to be deatroyed by the receipient?

I admit there is someone can live like a healthy person but the RBC is life shorten than normal , but this is rare and the destroy is not so strong .

If a gel crossmatch is incompatible but the result is inconsistent with other factors (i.e. the unit has been screened for all antigens to which the patient has identified antibodies), our investigation includes a DAT on the unit, and we have found some to be positive. Just to be on the safe side, we return these to the Blood Center and they issue credit. We don't routinely screen units for positive DAT.

None of any of my colleagues (who have worked in places that EI) have had any reports of transfusion reactions due to DAT postive donor units.

good morning

usually in our lab when we do cross matching , and give us positive , DAT wil be done for the unit , if its positive, we will discard it to be in safe side and cross match another unit for the patient .

DAT is not routien test for the donors.

Routine DAT testing is not required.

I think, as is the case with many questions, the answer is, it depends where you are. If you are in a country where the practice is to do a type and screen with electronic (rather than serological) crossmatch, then there is not really any point in doing a DAT routinely on your blood bags. If you are doing a serological crossmatch routinely, then it would be nice to know that your blood units had been tested and were DAT negative. This is not because of any possible damage a DAT-positive unit might cause to the patient; there is no evidence that I am aware of that any harm can be done. It is simply to avoid having to waste time investigating a positive crossmatch in the absence of a positive antibody screen. It is worth remembering that many laboratories who still perform the serological cross match routinely are in countries where there can be higher frequency of certain antigens that would normally be considered as low frequency in Europe and are therefore not present on the screening cells (such as the Miltenberger antigens or Dia or Jsa); in fact some of the labs in some of these countries would still ONLY do a crossmatch and not do an antibody screen at all. Granted, you can just crossmatch another unit, but it is still a waste of time and resources, with a patient on the other end maybe desperately waiting for his blood bag...