Does anyone collect and transfuse platelets less than 3.0E+11?

If so, how are you labeling these products according to:

• ISBT
  
• FDA Requirements: The platelet yield must be on the label for products less than 3.0
  

Thanks again

Stephanie

We use the following ISBT codes: E4643, E4644, E4645, and E4646. We label all of our platelets with the actual yield by using an additional label on the bag.

We use the following ISBT codes: E4643, E4644, E4645, and E4646. We label all of our platelets with the actual yield by using an additional label on the bag.

Do you have a low count threshold for these products where you wouldnt label/distribute them? Also, do you collect data to determine how many of these products you are collecting and the reason(s) why they do not meet the 3.0E+11 threshold?

When I was previously over the QC lab at a blood center, we used the cutoff of 2.7 as it was within 10% of the 3.0 cutoff. This was something that our medical director came up with so nothing writen in stone. We tracked data for low counts to look at equipment trends and tried to make sure that it was not instrument or tech related. We did find a couple of instrument problems this way but often this can be donor related as well. Some donors just are stingy with their plts and you have to adjust the target level up for these individuals.

@MHC, we usually discard a product if the yield is below 1.5. Most of the time (and they a re rare), the lowest yields are due to procedures that are discontinued before the target due to donor reactions/incidents. Most of our products that are labeled with the Variable Yield codes are >2.5.

I am curious if anyone else performs a post sampling yield. When we have an initial platelet yield between 2.5 and 3.2, we recalculate the platelet yield using the new volume after the sample for the initial platelet concentration and bacterial detection (and sometimes monthly QC) have been used. We have a few 3.2 X 10^11 platelets that end up being 2.9 X 10^11 low yield platelets based on the actual volume of the platelet prior to distribution. We utilize platelets with yields between 2.5 and 2.9 and label them an E4643V00 affixed with tie tag stating the yield. We discard anything with yields less than 2.5 unless a physician specifically requests it. We come so close to the 10% allowable volume variation that we perform recalculations for all platelets within the aforementioned range. Does anyone else do this?