w to the forum..have several questions

Hello,

I just joined this site and have several complicated medical questions. I will start with a brief history....Four years ago I was diagnosed with (AVWS) Acquired von willebrand syndrome and monoclonal gammopathy (pre-cancerous condition for Multiple Myeloma and a few other blood cancers. I had to have hysterectomy, so I had to receive 7 days of IVIG (immunoglobulins) with steriods to get my blood to clot enough to get through the surgery. They also pre-treated me with IV benadryl. I became very ill, but I guess fooled everyone because of the steriods and I did not know any better. The hematologist who was treating me had never met me before this. I have not been back to a hematologist since. According to my blood tests.. my RBC where getting detroyed and I was getting anemic and going into renal failure. (I still bleed in the surgery) My labs stated that a tested positive for a antibody. (had a transfusion in 2001 for a un-diagnosed internal bleeding) My questions are...Do I still have the antibody? Was the reaction from a virus, steriods, IVIG? Here is what my labs stated.....I will start will the CBC..High WBC..low RBC, low HGB, low HCT. Also it said present in my blood smear...macrocytosis, microcytosis, ovalocyte, toxic granulation. On another page it also said moderate hemolyzed specimen. I was not treated for the complications. Was the antibody temporary? Will I ever be able to use IVIG if I ever need any dental or surgeries? Thanks so much for any input! I forgot to mention my labs also said...antibody ID result 1, antigen type res 1, patient types FYA/(DUFFY A) antigen negative. I am 0+.. RH Postive.

Hello, I am the complicated person back for more of your thoughts. Its about my bone marrow biopsy from 2006! I went to another doctor and they did a skeletal survey and they looked at my BMB from 2006...no labs $$$. Well, I have alot more questions that the new doc could not answer...like the others! Ug. My blood smear was done by a different person that did the BMB. I have stated how bad my blood smear was listed above. So, I read the report about the 200 BMB. Now I am really confused. Of course the new doc had no clue either! Well anyway..its says 30% hypocellular marrow/should be 50%/ mild plasmacytosis and increased reticulin fibrosis. Now, I have never been told why I had all the blood smear abnormalaties. But, does this have any reflect of my BMB? Would this explain why I was so sick when I was getting IVIG treatments? I am still chasing my tail to get to the bottom of why I feel so darn bad all the time but my labs fool everyone. Thanks for any help!

Sorry to disappoint you but Medical Technologists are not "allowed" to diagnose. You need an MD for that. My state license is quite strict in that regard.

Good luck.

I was not asking for a diagnoses!!!!!!!!!!! Boy this is so typical of the medical industry......the gift that keeps giving! Not!

I was not asking for a diagnoses!!!!!!!!!!! Boy this is so typical of the medical industry......the gift that keeps giving! Not!

Everyone here has been so helpful explaining my antibodies. So, any additional info...send me email!