Can anyone tell me if they routinely perform an elution on a cord blood when you know the mom's plasma contains anti-D due to RhIg and/or there is an ABO incompatibility between mom & baby (ie: mom's group O and baby's group A)?

We do not do an elution when the positive DAT is likely to be ABO related (O mother has an A or B baby) or due to RhiG. The treatment in those cases is the same the doctor only has to monitor the bilirubin to determine if more time under the light is needed.

We do the same as PaulSunV.

My pedi Docs like to have elutions done . . . so we do them.

We have always done eluates on newborns with positive DATs.... a freeze-thaw when we suspect an ABO antibody, and an acid eluate when we suspect anything else. We are also looking to discontinue them. Thoughts??

We do acid elutions on all inpatient positive neonatal DATs (<4 months old). For outpatients, we just add a canned comment that says to contact the TS if further testing is desired.

A lot of adult hospitals don't do them if it looks like ABO ab or if the maternal ab is already known. We are a children's hospital (not a delivery hospital), so we don't always get the maternal ab information and don't like to "trust" the information provided by another TS or physician.

We do not do an elution for either situation.

Thank you all for your responses.