We had a case of coagulopathy due to liver disease and the patient was bleeding.. There ws shortage of A+ve PRBC so we had to swithch to O+ve PRBCs.

Male patient

5 units of O+ve compatible PRBCs transfused sucessfully.

After 2 days more demand for blood.

DAT on the patient 2+ in gel.. Do we go for O+ve or can we shift back to A+ve?

It surely depends upon what you elute from the patient's red cells.

If you elute anti-A, then go back to A.

If you elute off another specificity, you can use group O antigen negative blood - but, personally, I wold go back to the patient's own ABO group as soon as possible.

Most of the rbcs in the US are leukoreduced/additive solution rbcs. The amount of residual plasma in these units is negligble. I would switch back to the pts original blood type. Did you do an elution study?

Sorry!

Edited December 3, 201014 yr by khalidm3

We had a case of coagulopathy due to liver disease and the patient was bleeding.. There ws shortage of A+ve PRBC so we had to swithch to O+ve PRBCs.

Male patient

5 units of O+ve compatible PRBCs transfused sucessfully.

After 2 days more demand for blood.

DAT on the patient 2+ in gel.. Do we go for O+ve or can we shift back to A+ve?

Perform elute studies if u have not yet. Perform complete cross-match with A+ PRBC if u had used PRBC without additive other wise just shift to A+. What is the pre-transfusion DAT.

I have to ask, O+ve, what's ve? :confuse:

Short for, in this case, positive (+ve) (and -ve is short for negative).

We had a case of coagulopathy due to liver disease and the patient was bleeding.. There ws shortage of A+ve PRBC so we had to swithch to O+ve PRBCs.

Male patient

5 units of O+ve compatible PRBCs transfused sucessfully.

After 2 days more demand for blood.

DAT on the patient 2+ in gel.. Do we go for O+ve or can we shift back to A+ve?

Did the patient receive any group A PRBCs prior to having been switched to Group O? If so, and if you elute anti-A, you might want to check to see if the patient is a subgroup of A before considering switching back to A cells.

If the A cells are serologically compatible, I suggest switching back to A.