Some basic info--

A 38 year old Caucasian male patient was diagnosed with IgA nephropathy & renal arteriosclerosis and ending up developing hypertension and end stage renal disease in 2007.

In 2008 he was elected for a living related kidney transplant. During the transplant he had hemorrhaging which resulted in 2 liters of lost blood. He had 8 liters of crystalloid fluid, 4 liters of colloid fluid, and 4 units of PRBC's transfused within 60 minutes.

I'm thinking circulatory overload for sure but the case study mentions to look up TRALI as a possible cause of death. They also had talked about the patient being typed A+ and in his post mortem autopsy they never did a DAT.

So what are the similarities and differences of TRALI and TACO?

How can I narrow it down to one or the other?

I've been searching in the internet and haven't found much information on the two that can help me present this to a group clearly.

If you want the full case study for a better insight than my brief, ask and I will post it.

Any help would be greatly appreciated!

Send me your email in a PM and I'll send you a good reference.

testing for BNP(Brain natriuretic peptide) can help a little.