Given a standard volume for exchange, what is the ratio of red cells to plasma, 50/50?

VH

What the requirements for an exchange unit? Must it be washed, irradiated, and sicklecell neg?

Given a standard volume for exchange, what is the ratio of red cells to plasma, 50/50?

VH

Surely, it depends upon the circumstances? Are you talking about an exchange transfusion at birth for HDN, or an exchange transfusion in a child or adult with, for example, sickle cell disease?

:confused::confused:

What are the requirements for the unit of rbcs when reconstituted for an exchange to a neonate?

We require the MD to request an hematocrit. It may differ for an adult, child or neonate.

I have attached an abbreviated version of a procedure for preparing reconstituted whole blood for exchange transfusion for infants or for sickle cell patients.

The calculations are slightly different than some references, but they yield more accurate results when you are trying to achieve a specific hematocrit. The formula is based on trial and error and actual measurements of specific gravity, donor bags, etc.

rwb.pdf