Criteria of of releasing emergency blood .why o negative is given to female < 50 years old

and o positve to female > 50 years old does anyone has any ideas about this please share

thanks

edith:)

Criteria of of releasing emergency blood .why o negative is given to female < 50 years old

and o positve to female > 50 years old does anyone has any ideas about this please share

thanks

edith:)

This is all to do with the relative rarity of group O D Negative blood (roughly about 7.2% of the White population, and rarer in other populations).

The D antigen is the most immunogenic of all the red cell antigens (apart from ABO), which means that a person who is D Negative is highly likely to produce an anti-D if transfused with D+ blood.

Anti-D, in itself, is not dangerous, just because it is in the circulation. However, the antibody will cross the placenta and with destroy foetal red cells if they express the D antigen. Therefore, we try to avoid giving D+ blood to any female of "child-beariong potential" (horrible phrase), just in case they are D Negative.

Actually, in the UK, we would not consider giving group O D+ blood to a female in an emergency who is less than 60-years-old (and the same applies to K+), unless there was no other choice (i.e. the hospital had run out of group O D- blood, the lady was in danger of exsanguination, and no group O D- blood could be transported to the hospital in time to save her).

I hope this is of help.

:)

Hi Malcom,

Thank you so much for the information it is clear to me now .I appreciate it

Edith

My pleasure.

My BB policy is the same as Malcom's.