I am curious to see what the average dosage of cryoprecipitate is. At my hospital we currently dose depending on the weight of the patient but we are looking into standardizing the dose. We feel that on an average we transfuse pools of 6, any other doses out there? Thanks

We are an adult hospital. We transfuse in pools of 10 only. The physician does not order any particular dose, just a pool of cryo.

My response is the same as Cliff's.

We issue pool of 10 cryo. Our liver team ususally orders pool of 20.

We also issue a pool of 10 cryo.

With the advent of 5-packs of cryo from our supplier, five has become our standard dose. Previously, it was given in pools of 10.

I'm at a blood center and we currently pool 8 units of cryo. This is totally based on the pooling bag we have, not on any standard dose.

Some references will state 1 bag of cryo/7 kg of body weight, so you get the "standard" 10-unit dose for a 70 kg person. If someone's FBG is less than 90-100 mg/dL, with ongoing blood loss, you probably should give 15-20 units at a time.

MJ:cool:

We typically administer ten units of cryo, but in those circumstances with extended surgical times we typically give a dose of twenty units (especially to CABG/AVR patients).

We will give whatever the physician asks for, if they feel 5 is sufficient then we would pool 5, but generally speaking all of our physicians just automatically order a pool of 10 for everyone. Of course, this is strictly for adult patients.

We're the same as Bevydawn. The physician determines what they want and we provide it unless it just isn't quite right like the physician who ordered 1 unit of cryo for an adult. The medical director had a little chat with them and shortly the 1 had 9 friends in the bag with it.

At our institution, the physician determines the dose they want. Most of our physicians request 10 pooled. For bad cardiac cases, they sometimes request a pool of 20. We also occasionally get requests for a single cryo from the OR. They use it for glue to close up the surgical wound.

We don't do cardiac surgery or livers so we only give cryo for DIC. We have a calculation in our SOP for when the doc orders 2 units on an adult or something, but otherwise we do what the doc orders--often comes out to 6 units.

We routinely pool 10 Cryo units. We will do whatever the Dr. orders, like John S. stated, as long as the order is reasonable! We also have conversations with Dr's if they need a little help.