Mastering the DAT: A Deep Dive into 'Current Applications and Interpretations of the Direct Antiglobulin Test' (AABB, 1988)

📖 Book Review & Discussion: Revisiting the Direct Antiglobulin Test (DAT) – AABB 1988

The Direct Antiglobulin Test (DAT) remains crucial in immune-mediated hemolysis diagnosis, but its interpretation has evolved. This review examines the AABB publication Current Applications and Interpretations of the DAT (1988) and its relevance today.

🔬 Key topics include:
🩸 The predictive value of a positive DAT in different populations
🩸 Differentiating autoimmune vs. alloimmune hemolysis
🩸 Classic methodologies vs. modern techniques (solid-phase, flow cytometry)

🔗 Read the full review: [Mastering the DAT: A Deep Dive into 'Current Applications and Interpretations of the Direct Antiglobulin Test' (AABB, 1988)]

How do you approach weakly positive DATs? Have testing advancements changed your diagnostic approach? Let’s discuss!