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OB doctors order antibody testing on father of baby in HDFN cases--educational material?

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comment_91881

Some of our OB doctors are very confused about antigens vs antibodies and all of our case-sensitive allele terminology. They sometimes order antibody screens on fathers of babies carried by patients with antibodies capable of causing HDFN.  Or recently, a screen got ordered in error in addition to the antigen typing and the doctor was very confused why the father was positive for c & C but had a negative antibody screen. Before I try to write up something succinct for them (and their MAs and midwives), does anyone know of any materials like this already in existence? It probably needs to have images.  It can't get down in the weeds with us blood bankers. It needs to explain antigens and antibodies, alleles such as c & C, probably D and d genes, maybe how zygosity affects how baby inherits. 

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  • Malcolm Needs
    Malcolm Needs

    Andrew Hadley and Peter Soothill (Editors).  Alloimmune disorders of pregnancy.  Anaemia, thrombocytopenia and neutropenia in the fetus and newborn.  1st edition.  2002.  Cambridge University Press. 

  • John C. Staley
    John C. Staley

    Over the years have I discovered that information like this is best provided to physicians by physicians.  There were a few that recognized my knowledge and expertise on the subject but the vast major

  • Just a suggestion; see if your pathologist can find something that would/could be part of a physician's continuing education. The doctor's equivalent of our ASCP credits. 

comment_91884

Just a suggestion; see if your pathologist can find something that would/could be part of a physician's continuing education. The doctor's equivalent of our ASCP credits. 

comment_91895

Andrew Hadley and Peter Soothill (Editors).  Alloimmune disorders of pregnancy.  Anaemia, thrombocytopenia and neutropenia in the fetus and newborn.  1st edition.  2002.  Cambridge University Press.  ISBN: 0 521 78120 5.

Failing that, send them back to Nursery School, because it is THAT simple!

comment_91899

Over the years have I discovered that information like this is best provided to physicians by physicians.  There were a few that recognized my knowledge and expertise on the subject but the vast majority did not and some were even reluctant to get it from my blood bank medical directors.  I would recommend having your medical director provide the book recommended by Malcolm.  I wish I had a copy in my library when I was still working.  Good luck.  Let us know what you end up doing and how it goes.  I'm sure that this kind of problem will be with us for ever!

Malcolm, you are correct, the info is relatively simple.  It's getting them to step down, swallow their pride and listen that makes it difficult! 

:coffeecup:

 

 

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