Is there a reason to do additional testing (ie absorptions) on an eluate showing panagglutination?  We currently send a sample to our reference lab for further study, but wondering if there is any value in doing so.  This of course assuming we have successfully completed antibody ID on patients plasma, then discovered the panagglutinin on elution - should we hold up transfusion for reference lab testing?

I did allo-adsorptions on eluates for quite a while and never once detected anything in the adsorbed eluate.  My own experience suggests that it is a waste of time and resources, but others may disagree.

I agree with Malcom - not much value, if any. I, too, have done many such noninformative adsorptions.

In a recently-transfused patient, there is perhaps a very remote chance that (allo)adsorptions on an eluate would reveal a "only on the cells, not in the serum yet" newly formed antibody. This might be important if the clinicians suspect faster-than-normal red cell loss, but it would be very difficult to differentiate from the typical increased red cell demise seen in patients with warm autoantibodies.