Hi A pateint with macrogloubulinaemia, and has a strong IgM in his blood which didnt go with prewarmed tube method, I cant find compatible blood,, all the tests show strong agglutination even before adding AHG reagent,, we dont have DTT reagent to remove IgM from the plasma,,we transfused the patient with uncompatible but Rh group matching blood units a week ago and afraid that the patient developed alloantibodies,,, any ideas to how to remove IgM from the plasma:(:(