We are trying to see if other hospitals routinely perform titers-- either Isoagglutinin titers (for example, a recent patient receiving a mismatched BMT, our medical director wanted us to titer the patient's Anti-B before and after the transplant until it disappeared) and/or Antibody titers in pregnant women with CSA's. We routinely do OB Antibody titers and have just seen an increase in Isoagglutinin titers, and we were wondering what this information is actually used for, ie if they are really necessary or don't need to be done as often as they are ordered here at our facility. What are your experiences with this, if any?