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Malcolm Needs reacted to a post in a topic: BloodBankTalk: Clinical Aspects of Transfusion Reactions
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BloodBankTalk: Clinical Aspects of Transfusion Reactions
I just answered this question. My Score PASS
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Quotient BB reagents
We use 3 cell screen, 4 cell screen, IgG check cells and A1 and B cells for tube tests, plus a few of the monoclonal antisera. Only negative comment I have received from staff is that the IgG check cells tend to be weaker than Immucor, more like 2-3+ rather than 3-4+. Saved a lot of money making this switch, and we are looking at changing a few more reagents in 2019.
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O Pos vs O Neg red cells for emergencies
We start with O Pos for males and females 50+.
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Culture of blood products
We are a hospital system with 8 hospitals; the main facility has a microbiology department. When blood product cultures are required due to febrile transfusion reactions, our community hospitals send several pigtails for culture. This is not a great sample as it is not exactly what is in the bag, but transport of an open blood product is difficult and a potential biohazard. Is there an easy/safe way to send the entire "open" bag, or a product that could be used to create an acceptable sample? Appreciate any ideas!
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FDA Registration
Can anyone clarify? We are a hospital system with 6 sites/BBTS. We do not collect any blood products but do split and thaw products. Recently our blood supplier stated that if we "create" thawed plasma, which is an unlicensed product, we would need to register with the FDA. There is also some question regarding registration if the product is transported outside the thawing facility. Does anyone know for sure if FDA registration is required? Thanks!
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RBCto FFP ratio
We use 6RBC:4 FFP, platelet every other and Cryo as needed as well.
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CAP Inspection Question
We started doing random transfusion audits that are reviewed monthly by Quality Management, Transfusion Committee and Nursing Leadership. It has helped a lot!
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No Reactivity with Complement Control Cells
The package insert for the Immucor complement control cells states that "agglutination by anti-complement is seldom as strong as that customarily seen with anti-IgG and is more readily dispersed". Our expected QC result for anti-complement QC is W+-1+. I like this control because it also QCs the techs ability to not "over-shake" in tube testing, and ability to detect weakly reactive agglutination.