yolis76

Calling someone Rh neg who types 2+ with Anti-D must mean that your supplier is rich in Rh neg blood.....

I AGREEEEEEE!!!! Here's another example: I have a patient with a positive screen. Solid phase cell number one (E-e+, K+k+) is neg, cell two (E+e-, K-k+) is 2+. This makes you think Anti-E right? The techs ran the ID panel and the only cells that reacted were 2 out of the three K+ pos cells. The tech then ran the Extend I panel and, again, the only cells that reacted were 2 out of the 4 K+ cells. E was ruled out on 4 cells in solid phase. How can that be? I think were are missing an Anti-E, but how can I prove it when the only cell that reacted was the one cell in the screen? Nothing reacts in the tube, and this patient is pregnant. SOLID PHASE IS A WASTE OF TIME AND MONEY, in my honest opinion.....

This SBB program has since been moved to Rush University. Please see below: Veronica N. Lewis, MS, MT(ASCP)SBB Assistant Professor Director, Specialist in Blood Bank Certificate Program Department of Clinical Laboratory Sciences Rush University, 1021B-AAC 600 South Paulina Street Chicago, IL 60612 Phone: 312-942-2402 Fax: 312-942-6464 E-mail: Veronica_Lewis@rush.edu

I personally DO NOT LIKE solid phase for the very reasons that you listed. We encounter all of those issues, and it can feel like we are chasing our tails trying to find something that's not there. About your issues with antibodies that are only reacting in SP, that's to be expected. You are using a more sensitive method and its possible that antibodies that are not detecable in the tube will be picked up in SP. All you can do is honor the antibody and give Ag neg units. I would not recommend doing XMs in SP because then you'll be looking for trouble. About those situations in which you're sure you've identified an antibody and then the patient is ag+, its possible you've found a rare occurrence of an autoantibody with specificity other than Rh. The fact that the screen was neg later doesn't mean anything - once you've worked with SP some more you'll realize that the results are not reproducible, even on the same day with the same reagent and sample. It's frustrating, but I think SP is simply too sensitive.....