We QC each rack in use once each day. A new vial is not QC'd when opened until the daily QC is done. We do a QC on each panel when it arrives and check one cell with anti-K and another cell with anti-M. Panels are visually checked for hemolysis before put into use. Heterozygous cells positive and a negative cell are run with other typing reagents once each day and again at the discretion of the tech, sometimes just a positive.