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Hi from Canberra Australia - it is comforting to know that you guys face the same dilemma in the US with the KB tests as us here in OZ - everyone hates counting them - and on most surveys I end up sending in my result as most people over estimate & even though we have a flowcytomer here in the lab - we perform 8 survey quantitations a year but probably only need to quantitate 2 or 3 patients a year so it would be is very costly to just move it over to flow - even just to score better on our surveys! -
We have recently turned up two cases of unexpected antibodies in our Elutions. The first case we eluted an Anti-Fya from the red cells of a patient that had not been transfused for 5 years. (The tests were repeated & the control wash was always negative) From the papers I have read - it seems to me that Mimicking Antibodies are of a single specificity (or "wrong specificity" as described by most authors & can be absorbed using phenotypically negative cells ) and are a separate entity from those deemed to be resulting from the Matuhasi Ogata Phenomenon which requires the presence of an additional autoantibody antibody. Some people regard any mimicking Ab to be just Matuhasi Ogata Phenomenon - a term that most authors seem to give very little credence to these days I am a little puzzled are they one in the same thing?