If your auto-antibody is that weak (weak results only with red cells not expressing the antigen against which the antibody is directed), then I would think that the titre that you get with red cells that do express the antigen against which the antibody is directed would be fairly accurate, with not much in the way of boosting by the auto-antibody. The problem with performing an alloadsorption first, to get rid of the autoantibody (and, because the patient is pregnant, an autoadsorption is out of the question), prior to performing the titre, is that, however careful you are getting the alloadsorption red cells as packed as possible, you will get some dilution due to the medium in which the alloadsorption red cells are suspended. So, to a certain extent, you pays your money and you takes your choice as to whether you want a very slight boost to the titre by ignoring the very weak auto-antibody, or you want a very slight dilution after alloadsorption, bringing down the titre very slightly.