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Autocontrol positive .negative cross matching

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Can the autocontrol is positive , negative with cell of antibody screening cells and compatible cross match with RBCs units ?

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If the patient has received transfusion, the transfused antigens pos cells can cause the autocontrol mixed field positive, and when the antibodies are against some low prevalence antigens, then the reaction with screening cells and donor cells can get a neg reaction.

Or some drug induced antibodies can cause this kind of reaction because they are drug dependent.

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On 12/15/2018 at 2:46 PM, yan xia said:

If the patient has received transfusion, the transfused antigens pos cells can cause the autocontrol mixed field positive, and when the antibodies are against some low prevalence antigens, then the reaction with screening cells and donor cells can get a neg reaction.

Or some drug induced antibodies can cause this kind of reaction because they are drug dependent.

In addition to the scenario that Yan has describe above, I would like to add awarm autoantibody, where the antibody is saturated on the patient's own cells but has not "spill" into the plasma, therefore DAT and autocontrol may be positive but non-reactive with reagent red cells. 

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