Jump to content

Lewis exclusions


Tabbie

Recommended Posts

Hi All

Lewis antibody exclusions.

Realise they are rarely clinically significant only causing HTR and would perform crossmatch compatible. However I want to clarify the theory for exclusions.  

Human Anti-Lea is found in Le(a-b-) however exception to rule in Tawain where 10 Lea (a-b+) patients with anti-Lea were found. Most anti-Lea contains weak anti- Leb causing false positives.

However monoclonal reagents seem to indicate no cross reactivity? What reagents do you use to exclude the presence of either anti-Lea or Leb ? 

Thanks

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Recently Browsing   0 members

    • No registered users viewing this page.
  • Advertisement

×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.