Jump to content

RHIG stored at room temperature for hours


simret

Recommended Posts

Is there a guideline for RHIG reissue where the RHIG was issued and was not injected into the patient and sent back to Blood Bank? Note the RHIG ( Rhogam, Rhiphylac) was at room temp for hours? What does FDA/ AABB and CAP say besides to the manufacturer's insert?

Thanks,

Link to comment
Share on other sites

20 minutes ago, David Saikin said:

What does the pkg insert say?  How many hours?  I'd be inclined to toss the product.

I agree.  Quite apart from whether or not the immunoglobulin would actually be efficacious after hours out, within reason, the higher the temperature and the longer the immunoglobulin is outwith temperature range, the greater chance that, if there is any bacterial contamination, this will accentuate it, and possibly cause a fatal septicaemia.

Link to comment
Share on other sites

11 minutes ago, LIMPER55 said:

similar situation--Rn kept in her pocket for 12 hours after dispense.

I wrote technical service at Rhophylac company--they said no worries--should be fine.!!!

They said it, or they put it in writing?  If they did put it in writing, was the person who signed the letter senior enough to so do?

Link to comment
Share on other sites

On 6/7/2018 at 12:27 PM, Malcolm Needs said:

I agree.  Quite apart from whether or not the immunoglobulin would actually be efficacious after hours out, within reason, the higher the temperature and the longer the immunoglobulin is outwith temperature range, the greater chance that, if there is any bacterial contamination, this will accentuate it, and possibly cause a fatal septicaemia.

Fatal septicaemia?  The injection is IM not IV.  Malcolm don't you think that a septiceamia is a bit of a stretch.  I would think that a nasty cellulitis is more likely and if left untreated could be very serious or even fatal depending on the bug involved.  

I appear to be feeling just a bit argumentative today, good thing my lovely wife is off visiting family for a few days.  :rolleyes: 

Link to comment
Share on other sites

28 minutes ago, John C. Staley said:

Fatal septicaemia?  The injection is IM not IV.  Malcolm don't you think that a septiceamia is a bit of a stretch.  I would think that a nasty cellulitis is more likely and if left untreated could be very serious or even fatal depending on the bug involved.  

I appear to be feeling just a bit argumentative today, good thing my lovely wife is off visiting family for a few days.  :rolleyes: 

Fair comment John, not fatal septicaemia, just fatal cellulitis!  My point was though, that it is just not worth taking the risk.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Recently Browsing   0 members

    • No registered users viewing this page.
  • Advertisement

×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.