Enzyme treated panel cells

[BBNC17]

We currently have a ficin-treated panel from Immucor and the papain-treated panel from Quotient.  We have a tech that claims they used PEG with enzyme-treated panel cells at their previous job.  Is this necessary?  Their rationale was, since the panel has 10 untreated cells and then 10 enzyme-treated of those same cells, so they would run both the untreated and treated in PEG and perform a rule-out based on comparing the reactions.  

The package insert from Immucor says to not use potentiating reagents and the Quotient package insert says you may use potentiating reagents.

I've always thought of enzyme treatment as a potentiating reagent for certain antigen groups, so why would you need to need to add PEG and risk diluting out a possible antibody?

Thanks for any assistance!

[Malcolm Needs ☆]

You shouldn't.