Okie Posted July 25, 2017 Share Posted July 25, 2017 We have a patient who has both a cold and a warm autoantibody. It has been difficult to get a complete adsorption. Her HEA shows she is negative for Joa. Has anyone had patients negative for this, and if so, what transfusion practices did you follow? Thanks. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted July 26, 2017 Share Posted July 26, 2017 I have seen one in a hospital setting (she was pregnant). Her antibody was very weak (and no Jo(a-) blood was available in the UK anyway, apart from a couple of units of Gy(a-) that we ahd frozen down) and, if she had required transfusion, we would have been quite happy to have given "least incompatible). As far as I know, anti-Joa has never been implicated in a clinically significant transfusion reaction (and certainly not HDFN), although it was reported that one patient, when trialed with radio-labelled red cells, destroyed Jo(a+) red cells more rapidly than Jo(a-) red cells. Desoki 1 Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now