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Anti-D specificity reactive IAT only


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Yes - however, I would have expected an increase in the reaction with the R2R2 cell in the enzyme-IAT and it did not move.  Or did it go from a weak 1+ to a strong 1+.  Even so - for a 1+ in IAT, I would expect a +++ in an enz-IAT for a  'normal' anti-D.

Which country is this in?

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History History History pregnancies, transfusions, daddies, medications, High BP?   Early autoantibody,  early autoantibody mimicking anti-D?  One pathologist I have worked with considered pregnancy a disease, you may have some non-red cell stimulated mimicking antibody specificities due to a hyped up immune system.  We have seen an Anti-K titer rise during the pregnancy only to find the subsequent child and daddy to be Kell negative.

Would be nice to be able to follow patient, antibody detections, titers, Rh-hr typing of infant, etc...................  make a good abstract case presentation at a meeting.....

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  • 3 months later...

We have received a further sample from this patient but it is now further complicated by the fact she has now been given anti-D prophylaxis. It is a very interesting case and I would have liked to follow it through however I no longer work in the lab. Thank you for all your input.

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